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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEK3 All Species: 36.06
Human Site: Y168 Identified Species: 79.33
UniProt: P51956 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51956 NP_001139571.1 506 57705 Y168 T Y V G T P Y Y V P P E I W E
Chimpanzee Pan troglodytes XP_001160306 495 56653 Y162 P M A F A C T Y V G T P Y Y V
Rhesus Macaque Macaca mulatta XP_001106955 504 57509 Y168 T Y V G T P Y Y V P P E I W E
Dog Lupus familis XP_543184 1286 146207 Y169 T C I G T P Y Y L S P E I C E
Cat Felis silvestris
Mouse Mus musculus Q9R0A5 511 57204 Y166 T Y V G T P Y Y V P P E I W E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513217 507 57493 Y168 T Y M G T P Y Y V P P E V W E
Chicken Gallus gallus XP_001232686 498 56944 Y168 T Y V G T P Y Y V P P E I W E
Frog Xenopus laevis Q7ZZC8 944 104521 Y199 T C V G T L Y Y M S P E I C Q
Zebra Danio Brachydanio rerio Q90XC2 697 76523 Y169 T V V G T P C Y I S P E L C E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9CAU7 606 68016 Y169 S V V G T P S Y M C P E L L A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48479 858 94329 Y201 T Y V G T P F Y M S P E I C A
Conservation
Percent
Protein Identity: 100 96.8 95.4 22.4 N.A. 72.9 N.A. N.A. 74.5 62.2 21.2 24.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.2 96.8 31.6 N.A. 82.9 N.A. N.A. 86.3 76.4 34.2 40.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 66.6 N.A. 100 N.A. N.A. 86.6 100 60 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 80 N.A. 100 N.A. N.A. 100 100 73.3 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.9 N.A. 23
Protein Similarity: N.A. N.A. N.A. 47.5 N.A. 37.5
P-Site Identity: N.A. N.A. N.A. 46.6 N.A. 66.6
P-Site Similarity: N.A. N.A. N.A. 66.6 N.A. 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 19 % A
% Cys: 0 19 0 0 0 10 10 0 0 10 0 0 0 37 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 91 0 0 64 % E
% Phe: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 91 0 0 0 0 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 10 0 0 0 64 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 10 0 0 10 0 0 0 19 10 0 % L
% Met: 0 10 10 0 0 0 0 0 28 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 82 0 0 0 46 91 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 0 0 0 0 10 0 0 37 0 0 0 0 0 % S
% Thr: 82 0 0 0 91 0 10 0 0 0 10 0 0 0 0 % T
% Val: 0 19 73 0 0 0 0 0 55 0 0 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 46 0 % W
% Tyr: 0 55 0 0 0 0 64 100 0 0 0 0 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _